21st Century Nanotechnology Research and Development Act

21st Century Nanotechnology Research and Development Act - Directs the President to establish a National Nanotechnology Research Program. Requires such Program, through appropriate Federal agencies, councils, and the National Coordination Office, to: (1) establish goals, priorities, grand challenges (fundamental problems in science and engineering that will require the application of nanotechnology), and metrics for evaluating Federal nanotechnology research, development, and other activities; (2) invest in Federal research and development (R&D) programs in nanotechnology and related sciences to achieve those goals; and (3) provide for coordination of Federal nanotechnology activities.Requires the Program, through its participating agencies, to develop, fund, and manage Federal research programs concerning: (1) long-term basic nanoscience and engineering research; (2) essential grand challenges and interdisciplinary research and education teams; (3) interdisciplinary nanotechnology research centers; (4) research infrastructure and equipment; (5) the Center for Ethical, Societal, Educational, Legal, and Workforce Issues Related to Nanotechnology to be established by the Director of the National Science Foundation (NSF); (6) technology transition; and (7) research areas identified by the National Science and Technology Council (NSTC) which are not being adequately addressed by the agencies' current research programs.Directs NSTC to: (1) oversee the planning, management, and coordination of the Program; (2) establish an Information Services and Applications Council; and (3) submit an annual report to Congress on the Program..Directs the President to establish a National Nanotechnology Advisory Panel and a National Nanotechnology Coordination Office.Provides for the National Research Council of the National Academy of Sciences to conduct a triennial evaluation of the Program.Requires the NSF Director to: (1) collect and disseminate studies on the societal, ethical, educational, and workforce implications of nanotechnology; and (2) collect data on the size of the anticipated nanotechnology workforce needed and assess the adequacy of the trained talent pool to fill such needs.